[Perioperative antibiotic prophylaxis in breast surgery: cefotiam versus clindamycin]

Zentralbl Gynakol. 1996;118(5):279-82.
[Article in German]

Abstract

97 patients undergoing breast surgery received either 2 g cefotiam or 1200 mg clindamycin as i.v. singleshot application in the course of an open randomised comparison of parallel groups to evaluate the efficacy and tolerability of both antibiotic regimens. Both regimens proved to be well to-lerated and equally suitable for the prophylaxis of postoperative infections in breast surgery.

Publication types

  • Clinical Trial
  • Comparative Study
  • English Abstract
  • Randomized Controlled Trial

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Antibiotic Prophylaxis*
  • Cefotiam / adverse effects
  • Cefotiam / therapeutic use*
  • Clindamycin / adverse effects
  • Clindamycin / therapeutic use*
  • Dose-Response Relationship, Drug
  • Female
  • Humans
  • Infusions, Intravenous
  • Mammaplasty*
  • Mastectomy*
  • Middle Aged
  • Reoperation
  • Risk Factors
  • Surgical Wound Infection

Substances

  • Clindamycin
  • Cefotiam