Neurotoxicity of Cyclosporine A in therapy of steroid resistant nephrotic syndrome in a 10-year old boy

Abstract

A 10-year old boy with steroid resistant nephrotic syndrome developed neurological symptoms during the combined therapy with Cyclosporine A, prednisone and ketonazole. These symptoms might be caused by Cyclosporine because the clinical course and laboratory data revealed neither inflammatory nor other causative factors.