Abstract
A new low-toxic antimicrobial preparation is proposed to impregnate woven materials used in treatment of pyo-inflammatory wounds contaminated with Gram-positive and Gram-negative bacteria as well as with pathogenic fungi as a result of an artificial infection. Sodic form of sudamate is less toxic, its bactericidal effect being 3-5 times more effective than that of hexachlorophene.
Publication types
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Comparative Study
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English Abstract
MeSH terms
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Animals
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Anti-Infective Agents, Local / therapeutic use*
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Anti-Infective Agents, Local / toxicity
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Bandages
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Candidiasis / drug therapy
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Cells, Cultured
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Drug Evaluation, Preclinical
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Gram-Negative Bacterial Infections / drug therapy
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Gram-Positive Bacterial Infections / drug therapy
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Guinea Pigs
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Hexachlorophene / therapeutic use
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Hexachlorophene / toxicity
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Humans
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Male
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Organic Chemicals
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Rats
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Sodium / therapeutic use*
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Sodium / toxicity
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Wound Infection / drug therapy
Substances
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Anti-Infective Agents, Local
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Organic Chemicals
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sudamate
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Sodium
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Hexachlorophene