Recent developments in theories of pathogenesis of AIDS

Trends Microbiol. 1996 Jul;4(7):282-5. doi: 10.1016/0966-842x(96)10044-5.

Abstract

Experimental and theoretical progress in HIV research includes an improved resolution of the spatial heterogeneity and the dynamics (time course and turnover rates) of virus and CD4+ cells. Some of these advances have resulted from the joint work of experimental and theoretical groups, demonstrating that interdisciplinary research can be fruitful.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Acquired Immunodeficiency Syndrome / etiology*
  • Acquired Immunodeficiency Syndrome / immunology
  • Antigens, Viral
  • CD4-Positive T-Lymphocytes / immunology
  • Disease Progression
  • HIV / pathogenicity*
  • HIV Infections / immunology
  • Humans
  • Immunodominant Epitopes
  • Lymphoid Tissue / virology
  • T-Lymphocytes, Cytotoxic / immunology

Substances

  • Antigens, Viral
  • Immunodominant Epitopes