Pharmacological characterization of glial cell line-derived neurotrophic factor (GDNF): implications for GDNF as a therapeutic molecule for treating neurodegenerative diseases

Cell Tissue Res. 1996 Nov;286(2):179-89. doi: 10.1007/s004410050687.

Abstract

This review presents a comprehensive survey of the recently described pharmacological activities of glial cell line-derived neurotrophic factor on the central nervous system.

Publication types

  • Review

MeSH terms

  • Animals
  • Glial Cell Line-Derived Neurotrophic Factor
  • Humans
  • Nerve Degeneration / drug effects*
  • Nerve Growth Factors / pharmacology*
  • Nerve Tissue Proteins / pharmacology*
  • Nervous System Diseases / drug therapy*
  • Neuroprotective Agents / pharmacology*

Substances

  • GDNF protein, human
  • Glial Cell Line-Derived Neurotrophic Factor
  • Nerve Growth Factors
  • Nerve Tissue Proteins
  • Neuroprotective Agents