Accumulation of Tc-99m HMDP in hepatic metastasis from colon carcinoma without detectable calcification

Ann Nucl Med. 1996 Aug;10(3):347-9. doi: 10.1007/BF03164744.

Abstract

A 51-year-old man was found to have hepatic metastasis from colon carcinoma. Bone scintigraphy with 99mTc-hydroxymethylene diphosphonate showed a ringlike accumulation corresponding to the hepatic mass, which was without calcification on computed tomography. Treatment with chemotherapeutic agents was started. After 4 months, computed tomography showed that the mass was smaller than before and that the margin was calcified. The extraosseous accumulation of the radionuclide may be evidence supporting earlier speculation on calcification that could not yet be detected by computed tomography.

Publication types

  • Case Reports
  • Comparative Study

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Bone and Bones / diagnostic imaging
  • Calcinosis
  • Cisplatin / administration & dosage
  • Colonic Neoplasms / diagnostic imaging*
  • Colonic Neoplasms / drug therapy
  • Fatal Outcome
  • Fluorouracil / administration & dosage
  • Humans
  • Liver Neoplasms / diagnostic imaging*
  • Liver Neoplasms / drug therapy
  • Liver Neoplasms / secondary*
  • Male
  • Middle Aged
  • Technetium Tc 99m Medronate / analogs & derivatives*
  • Technetium Tc 99m Medronate / pharmacokinetics
  • Tomography, Emission-Computed
  • Tomography, X-Ray Computed

Substances

  • technetium Tc 99m hydroxymethylene diphosphonate
  • Cisplatin
  • Fluorouracil
  • Technetium Tc 99m Medronate