Regulation of the kynurenine pathway by IFN-gamma in murine cloned macrophages and microglial cells

Adv Exp Med Biol. 1996:398:171-5. doi: 10.1007/978-1-4613-0381-7_28.
No abstract available

MeSH terms

  • 3-Hydroxyanthranilate 3,4-Dioxygenase
  • Animals
  • Brain / enzymology
  • Clone Cells
  • Dexamethasone / pharmacology
  • Dioxygenases*
  • Enzyme Induction
  • Interferon-gamma / pharmacology*
  • Kinetics
  • Kynurenine / metabolism*
  • Kynurenine 3-Monooxygenase
  • Lipopolysaccharides / pharmacology
  • Lyases*
  • Macrophages / drug effects
  • Macrophages / enzymology*
  • Mice
  • Microglia / drug effects
  • Microglia / enzymology*
  • Mixed Function Oxygenases / metabolism
  • Oxygenases / metabolism
  • Thymus Gland
  • Transaminases / metabolism
  • Tryptophan Oxygenase / biosynthesis*
  • Tumor Necrosis Factor-alpha / pharmacology

Substances

  • Lipopolysaccharides
  • Tumor Necrosis Factor-alpha
  • Kynurenine
  • Dexamethasone
  • Interferon-gamma
  • Mixed Function Oxygenases
  • Oxygenases
  • Dioxygenases
  • Tryptophan Oxygenase
  • 3-Hydroxyanthranilate 3,4-Dioxygenase
  • Kynurenine 3-Monooxygenase
  • Transaminases
  • glutamine - phenylpyruvate transaminase
  • kynurenine-oxoglutarate transaminase
  • Lyases