Enantiospecific synthesis and in vitro activity of selective inhibitors of rat brain kynureninase and kynurenine-3-hydroxylase

Adv Exp Med Biol. 1996:398:531-4. doi: 10.1007/978-1-4613-0381-7_83.
No abstract available

MeSH terms

  • Alanine / analogs & derivatives*
  • Alanine / chemical synthesis*
  • Alanine / chemistry
  • Alanine / pharmacology
  • Animals
  • Benzoates / chemical synthesis*
  • Benzoates / chemistry
  • Benzoates / pharmacology
  • Brain / enzymology*
  • Drug Design
  • Enzyme Inhibitors / chemical synthesis*
  • Enzyme Inhibitors / chemistry
  • Enzyme Inhibitors / pharmacology
  • Hydrolases / antagonists & inhibitors*
  • Indicators and Reagents
  • Kinetics
  • Kynurenine 3-Monooxygenase
  • Male
  • Mixed Function Oxygenases / antagonists & inhibitors*
  • Rats
  • Rats, Wistar
  • Stereoisomerism
  • Structure-Activity Relationship

Substances

  • Benzoates
  • Enzyme Inhibitors
  • Indicators and Reagents
  • Mixed Function Oxygenases
  • Kynurenine 3-Monooxygenase
  • Hydrolases
  • kynureninase
  • Alanine