[Improvement of thrombocytopenia by administration of M-CSF in a patient with relapsed Philadelphia chromosome-positive acute lymphoblastic leukemia]

Abstract

A 55-year old male, diagnosed as Ph1 (+) ALL in July 1992, subsequently achieved complete remission. However, he was admitted again in November 1993 because of relapse. Although blasts in bone marrow decreased following chemotherapy and G-CSF administration, thromocytopenia remained, and he needed platelet transfusions every other day. After he began receiving M-CSF, the platelet count increased and platelet transfusions became unnecessary. M-CSF may be useful for thrombocytopenia after chemotherapy in Ph1 (+) ALL.