Collection and normal levels of the amyloid precursor protein in plasma

S Whyte; N Wilson; J Currie; P Maruff; V Malone; R Shafiq-Antonacci; P Tyler; K L Derry; J Underwood; Q X Li; K Beyreuther; C L Masters

doi:10.1002/ana.410410122

Collection and normal levels of the amyloid precursor protein in plasma

Ann Neurol. 1997 Jan;41(1):121-4. doi: 10.1002/ana.410410122.

Authors

S Whyte¹, N Wilson, J Currie, P Maruff, V Malone, R Shafiq-Antonacci, P Tyler, K L Derry, J Underwood, Q X Li, K Beyreuther, C L Masters

Affiliation

¹ Department of Pathology, the University of Melbourne, Parkville, Victoria, Australia.

PMID: 9005877
DOI: 10.1002/ana.410410122

Abstract

The amyloid precursor protein is contained in platelet alpha granules and released with degranulation. Methods are described to control for amyloid precursor protein release from platelets during blood collection and processing. In normal subjects (n = 97; age range, 44-84 years), the average plasma level of amyloid precursor protein was 6.5 +/- 1.8 ng/ml.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adult
Aged
Aged, 80 and over
Amyloid beta-Protein Precursor / blood*
Female
Humans
Male
Middle Aged
Reference Values

Substances

Amyloid beta-Protein Precursor