[Lipogranuloma of the orbit. Apropos of a case]

J Fr Ophtalmol. 1996;19(12):780-4.
[Article in French]

Abstract

We present a case of orbital lipogranuloma with a supero-nasal retrobulbar localisation associated with axial proptosis and major choroidal thickening. No clinical sign of inflammation, neither orbital nor in the posterior segment, was revealed. The systemic work-up as well as paraclinical data were within normal limits. The diagnosis was made after histopathologic examination of the biopsy taken via superior orbit. Outcome was favorable following long-term systemic corticotherapy. Orbital lipogranuloma is a rare particular form of orbital pseudotumour of unknown etiology. It is characterized, histologically, by orbital fat necrosis. Pathogenesis remains controversial. The differential diagnosis includes iatrogenic lipogranulomas secondary to sinus surgery (paraffinoma), orbital granulomas in sarcoidosis and Wegener's disease and orbital lymphomas. The prognosis is usually good following treatment with steroids.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Adult
  • Anti-Inflammatory Agents / therapeutic use
  • Diagnosis, Differential
  • Female
  • Granuloma / diagnosis
  • Granuloma / drug therapy
  • Granuloma / pathology*
  • Humans
  • Methylprednisolone / therapeutic use
  • Orbital Diseases / diagnosis
  • Orbital Diseases / drug therapy
  • Orbital Diseases / pathology*
  • Orbital Neoplasms / diagnosis

Substances

  • Anti-Inflammatory Agents
  • Methylprednisolone