Verbal scales in the acute treatment of migraine: semantic categories and clinical relevance

Cephalalgia. 1997 Feb;17(1):37-9; discussion 2. doi: 10.1046/j.1468-2982.1997.1701037.x.

Abstract

Verbal scales are currently used as efficacy parameters in acute migraine trials. In order to determine the correlation between headache intensity, functional disability, and relevant pain reduction, 100 patients completed a questionnaire. Our results showed that a verbal scale of headache intensity alone has different implications from one that includes pain intensity and functional ability. The reduction from a moderate to a mild headache was satisfactory to only 35% of the patients. In contrast, 77% of patients were satisfied when the headache intensity was reduced from severe to mild. These findings imply that, in assessing the efficacy of drugs used for migraine, a reduction in pain intensity from moderate to mild should not be considered as a good outcome.

MeSH terms

  • Acute Disease
  • Adult
  • Aged
  • Clinical Trials as Topic
  • Female
  • Humans
  • Male
  • Middle Aged
  • Migraine Disorders / drug therapy
  • Migraine Disorders / physiopathology*
  • Pain Measurement*
  • Severity of Illness Index
  • Treatment Outcome