T cell receptor delta locus polymorphism in rheumatoid arthritis

Eur J Immunogenet. 1994 Dec;21(6):479-83. doi: 10.1111/j.1744-313x.1994.tb00221.x.

Abstract

In order to identify new susceptibility markers for Rheumatoid Arthritis (RA), we analysed the dinucleotide repeat polymorphism at the T cell receptor delta locus (TCRD) in 65 RA patients and 99 healthy Belgian controls. A significant under-representation of the A4-A5 TCRD genotype was observed in the RA population.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alleles
  • Arthritis, Rheumatoid / epidemiology
  • Arthritis, Rheumatoid / genetics*
  • Arthritis, Rheumatoid / immunology*
  • Base Sequence
  • Belgium / epidemiology
  • Case-Control Studies
  • DNA Primers / genetics
  • Dinucleotide Repeats
  • Gene Frequency
  • Genotype
  • HLA-DR4 Antigen / genetics
  • Humans
  • Polymorphism, Genetic*
  • Receptors, Antigen, T-Cell, gamma-delta / genetics*

Substances

  • DNA Primers
  • HLA-DR4 Antigen
  • Receptors, Antigen, T-Cell, gamma-delta