Angioedema associated with angiotensin II receptor antagonist losartan

South Med J. 1997 May;90(5):552-3. doi: 10.1097/00007611-199705000-00020.

Abstract

Angioedema has not been associated with losartan therapy in hemodialysis patients, as it has been with angiotensin converting enzyme (ACE) inhibitors. We report the case of a hemodialysis patient who previously had angioedema after therapy with ACE inhibitors and again had angioedema while taking losartan. We suggest caution in using losartan in patients with known sensitivity to ACE inhibitors manifested by angioedema.

Publication types

  • Case Reports

MeSH terms

  • Angioedema / chemically induced*
  • Angiotensin Receptor Antagonists*
  • Antihypertensive Agents / adverse effects*
  • Antihypertensive Agents / therapeutic use
  • Biphenyl Compounds / adverse effects*
  • Biphenyl Compounds / therapeutic use
  • Female
  • Heart Failure / drug therapy
  • Humans
  • Hypertension / drug therapy
  • Imidazoles / adverse effects*
  • Imidazoles / therapeutic use
  • Losartan
  • Middle Aged
  • Renal Dialysis
  • Tetrazoles / adverse effects*
  • Tetrazoles / therapeutic use

Substances

  • Angiotensin Receptor Antagonists
  • Antihypertensive Agents
  • Biphenyl Compounds
  • Imidazoles
  • Tetrazoles
  • Losartan