Deletion of p21 cannot substitute for p53 loss in rescue of mdm2 null lethality

Nat Genet. 1997 Aug;16(4):336-7. doi: 10.1038/ng0897-336.
No abstract available

Publication types

  • Letter
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Blastomeres / cytology
  • Blastomeres / metabolism
  • Blotting, Northern
  • Cyclin-Dependent Kinase Inhibitor p21
  • Cyclins / genetics*
  • Gene Deletion*
  • Gene Expression Regulation
  • Genes, Lethal*
  • Mice
  • Nuclear Proteins*
  • Proto-Oncogene Proteins / genetics*
  • Proto-Oncogene Proteins c-mdm2
  • Tumor Suppressor Protein p53 / genetics*

Substances

  • Cdkn1a protein, mouse
  • Cyclin-Dependent Kinase Inhibitor p21
  • Cyclins
  • Nuclear Proteins
  • Proto-Oncogene Proteins
  • Tumor Suppressor Protein p53
  • Mdm2 protein, mouse
  • Proto-Oncogene Proteins c-mdm2