Pharmacokinetics of [14C] BBR 3053, an alkylating bisphosphonate, after single i.v. and multiple s.c. administration in rats

Boll Chim Farm. 1997 Apr;136(4):304-7.

Authors

A Bernareggi¹, M T Crippa, U Bastrup, S Di Giovine, R Cesarini, S Tognella

Affiliation

¹ Boehringer Mannheim Italia SpA, Centro Ricerche, Monza (MI).

PMID: 9281891

No abstract available

MeSH terms

Animals
Antineoplastic Agents, Alkylating / administration & dosage
Antineoplastic Agents, Alkylating / pharmacokinetics*
Carcinoma 256, Walker / drug therapy
Carcinoma 256, Walker / metabolism
Diphosphonates / administration & dosage
Diphosphonates / pharmacokinetics*
Injections, Intravenous
Injections, Subcutaneous
Male
Rats
Rats, Sprague-Dawley
Tissue Distribution

Substances

Antineoplastic Agents, Alkylating
BBR 3053
Diphosphonates