Clearance of cervical human papillomavirus infection by treatment for cervical dysplasia

Sex Transm Dis. 1997 Sep;24(8):456-60. doi: 10.1097/00007435-199709000-00003.

Abstract

Objectives: The aim of this study was to investigate the prevalence of human papillomavirus (HPV) after treatment for cervical dysplasia.

Study design: The presence of HPV was investigated in cervical scrapes of 91 patients, before and after treatment, using consensus primers in the polymerase chain reaction.

Results: Before treatment for cervical dysplasia, 89 of 91 patients (98%) were HPV-positive compared with 28 of 91 patients (31%) after treatment. The HPV type present before treatment was found in the scrapes of only 9 of 89 patients (10%). Detection of HPV after treatment was associated with human immunodeficiency virus infection and incomplete conization.

Conclusion: The HPV type present before treatment was frequently cleared by treatment for cervical dysplasia.

MeSH terms

  • Adult
  • DNA, Viral / analysis
  • Female
  • Humans
  • Middle Aged
  • Molecular Sequence Data
  • Netherlands / epidemiology
  • Papillomaviridae / genetics*
  • Papillomavirus Infections / epidemiology*
  • Papillomavirus Infections / virology
  • Polymerase Chain Reaction
  • Prevalence
  • Prospective Studies
  • Tumor Virus Infections / epidemiology*
  • Tumor Virus Infections / virology
  • Uterine Cervical Dysplasia / complications*
  • Uterine Cervical Dysplasia / pathology
  • Uterine Cervical Dysplasia / therapy
  • Uterine Cervical Neoplasms / complications*
  • Uterine Cervical Neoplasms / pathology
  • Uterine Cervical Neoplasms / therapy

Substances

  • DNA, Viral

Associated data

  • GENBANK/X13294