Virulence patterns of Escherichia coli K1 strains associated with neonatal meningitis

J Clin Microbiol. 1997 Nov;35(11):2981-2. doi: 10.1128/jcm.35.11.2981-2982.1997.

Abstract

The prevalence of the ibe10 gene, of the pap, afa, and sfa adhesin-encoding operons, and of a 14.9-kb rrn-containing HindIII fragment was studied for 67 Escherichia coli neonatal meningitis strains, 58 E. coli K1 commensal strains, and 47 E. coli blood isolates from neonates without meningitis. ibe10, sfa, and the 14.9-kb HindIII fragment were observed significantly more often in the meningitis strains than in blood or commensal strains.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adhesins, Bacterial / genetics
  • Bacterial Proteins / genetics
  • Deoxyribonuclease HindIII
  • Escherichia coli / genetics
  • Escherichia coli / isolation & purification
  • Escherichia coli / pathogenicity*
  • Escherichia coli Infections / blood
  • Escherichia coli Infections / cerebrospinal fluid
  • Escherichia coli Infections / microbiology*
  • Escherichia coli Proteins*
  • Feces / microbiology
  • Genes, Bacterial
  • Humans
  • Infant, Newborn
  • Membrane Proteins / genetics
  • Meningitis, Bacterial / blood
  • Meningitis, Bacterial / cerebrospinal fluid
  • Meningitis, Bacterial / microbiology*
  • Operon*
  • Polymerase Chain Reaction
  • Restriction Mapping
  • Virulence

Substances

  • Adhesins, Bacterial
  • Bacterial Proteins
  • CusC protein, E coli
  • Escherichia coli Proteins
  • Membrane Proteins
  • Deoxyribonuclease HindIII