Immediate postoperative CT contrast enhancement following surgery of cerebral tumoral lesions

J Comput Assist Tomogr. 1998 Jan-Feb;22(1):120-5. doi: 10.1097/00004728-199801000-00022.

Abstract

Purpose: Our goal was to evaluate the immediate postoperative contrast enhancement behavior of cerebral lesions and to gain further information about contrast enhancement in patients under general anesthesia.

Method: In the early postoperative period, CT scans with the without contrast medium were performed in 46 patients. The time interval between surgery and postoperative CT imaging ranged from 1 to 7.5 h (mean 4 h). Nineteen patients were under general anesthesia during CT investigation.

Results: In the early postoperative period, contrast medium leakage into the tumor resection cavity was noted In 14 patients (30%). Another phenomenon that was observed was the appearance of a strong demarcation and distinct contrast of gray against white matter in 24 patients (52%). This characteristic, global contrast enhancement of the cerebral cortex, occurred in 17 of 19 patients (89%) investigated under general anesthesia.

Conclusion: In immediate postoperative CT scans, contrast medium leakage due to extravasation of contrast medium into the tumor resection cavity can be detected early. Moreover, a global contrast enhancement of the cerebral cortex can be detected as a frequent pattern in patients investigated under general anesthesia.

Publication types

  • Clinical Trial

MeSH terms

  • Adult
  • Aged
  • Anesthesia, General
  • Astrocytoma / diagnostic imaging
  • Astrocytoma / surgery
  • Brain Neoplasms / diagnostic imaging*
  • Brain Neoplasms / secondary
  • Brain Neoplasms / surgery
  • Cerebral Cortex / pathology
  • Contrast Media
  • Extravasation of Diagnostic and Therapeutic Materials / diagnostic imaging
  • Female
  • Glioblastoma / diagnostic imaging
  • Glioblastoma / surgery
  • Glioma / diagnostic imaging
  • Glioma / surgery
  • Humans
  • Male
  • Middle Aged
  • Postoperative Period
  • Prospective Studies
  • Radiographic Image Enhancement / methods*
  • Research Design
  • Tomography, X-Ray Computed*

Substances

  • Contrast Media