The problems of detection and treatment of patients with tuberculosis, which are of paramount importance for today, are presented through the analysis of the tuberculosis epidemic situation in the country and of the sociomedical characteristics of new cases (49% of socially disadapted persons). Of the most significance is the need to promptly identify patients with strains on their referral to the general somatic hospitals for complaints by using 3-multiple sputum bacterioscopy for Mycobacterium tuberculosis by the Ziehl-Neelsen method. The vital problem is also to change chemotherapeutical regimens as more severe progressive types of the disease require more active treatment in the first months after detection especially in the cohort of socially disadapted persons.