Preoperative staging of endometrial carcinoma: diagnostic effect of T2-weighted fast spin-echo MR imaging

Radiology. 1998 Feb;206(2):539-47. doi: 10.1148/radiology.206.2.9457210.

Abstract

Purpose: To evaluate the usefulness of T2-weighted fast spin-echo magnetic resonance (MR) imaging with a 512 x 256 matrix for assessment of the preoperative stage of endometrial carcinoma.

Materials and methods: Twenty-eight women with histopathologically proved endometrial carcinoma underwent preoperative T2-weighted fast spin-echo, dynamic T1-weighted fast spin-echo, and postcontrast T1-weighted spin-echo MR imaging with a phased-array surface coil. The uterine long-axis planes in each sequence were reviewed at separate sessions by three radiologists blinded to the histopathologic data.

Results: For the diagnosis of myometrial invasion, no statistically significant differences were found among T2-weighted imaging, dynamic imaging, and postcontrast T1-weighted imaging. For the diagnosis of deep myometrial invasion, T2-weighted and dynamic images showed higher specificity than postcontrast T1-weighted images (T2-weighted, 89%; dynamic, 88%; and postcontrast T1-weighted, 80%). For cervical invasion, T2-weighted and dynamic images showed larger areas under receiver operating characteristic curves than did postcontrast T1-weighted images (T2-weighted, 0.78; dynamic, 0.71; and postcontrast T1-weighted, 0.67).

Conclusion: T2-weighted imaging is useful for identifying the stage of endometrial carcinoma.

MeSH terms

  • Carcinoma / epidemiology
  • Carcinoma / pathology*
  • Carcinoma / surgery
  • Cervix Uteri / pathology
  • Contrast Media
  • Endometrial Neoplasms / epidemiology
  • Endometrial Neoplasms / pathology*
  • Endometrial Neoplasms / surgery
  • Endometrium / pathology
  • Female
  • Gadolinium DTPA
  • Humans
  • Magnetic Resonance Imaging / methods*
  • Middle Aged
  • Myometrium / pathology
  • Neoplasm Invasiveness
  • Neoplasm Staging
  • Preoperative Care
  • ROC Curve
  • Reproducibility of Results
  • Sensitivity and Specificity

Substances

  • Contrast Media
  • Gadolinium DTPA