Multiple-flip-angle, three-dimensional, time-of-flight magnetic resonance (MR) angiography was performed in vitro and in vivo in the carotid artery bifurcation. Composite MR angiographic images were created from multiple data sets. Compared with images obtained with a low (20 degrees) flip angle, composite images obtained with flip angles of 20 degrees and 60 degrees demonstrated improved image quality and statistically significant improvement in signal-to-noise ratio (P < .05).