Effects on left ventricular mass and function of low doses of enalapril for systemic hypertension

Am J Cardiol. 1998 Jan 1;81(1):87-90. doi: 10.1016/s0002-9149(97)00860-6.

Abstract

After 7 years of treatment with 20 mg of enalapril twice daily, regression of the initial left ventricular hypertrophy in a group of 24 patients with essential arterial hypertension was achieved: gradual reduction in the dosage to 10 or 5 mg twice daily caused no worsening of either blood pressure or ventricular structure or function.

MeSH terms

  • Adult
  • Aged
  • Antihypertensive Agents / pharmacology
  • Antihypertensive Agents / therapeutic use*
  • Blood Pressure
  • Echocardiography, Doppler, Pulsed
  • Enalapril / pharmacology
  • Enalapril / therapeutic use*
  • Female
  • Heart Rate
  • Humans
  • Hypertension / complications*
  • Hypertension / drug therapy*
  • Hypertrophy, Left Ventricular / diagnostic imaging
  • Hypertrophy, Left Ventricular / etiology*
  • Male
  • Middle Aged
  • Ventricular Function, Left / drug effects

Substances

  • Antihypertensive Agents
  • Enalapril