Abstract
We describe a case of Toxoplasma gondii lymphoadenopathy in an intramammary lymph node in a 22 year old woman. Clinical evidence and ultrasound were suggestive for fibroadenoma, while cytology on fine needle aspiration suspected a lymphomatous lesion. The pathological examination demonstrated a lymph node with granulomatous foci with epithelioid histiocytes, consistent with Toxoplasma gondii lymphadenopathy. The pathological finding was confirmed by serological tests and by PCR (Polymerase Chain Reaction) using specific primers designed on ribosomal 18s DNA sequence of Toxoplasma gondii. The aim of this work is to emphasize the role of molecular biology techniques as an aid to pathological diagnosis in parasite diseases.
Publication types
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Case Reports
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English Abstract
MeSH terms
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Adult
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Animals
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Breast Diseases / diagnosis*
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Breast Diseases / parasitology
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Breast Diseases / pathology
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Breast Neoplasms / diagnosis*
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DNA, Protozoan / analysis
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DNA, Ribosomal / analysis
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Diagnosis, Differential
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Female
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Fibroadenoma / diagnosis*
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Hodgkin Disease / diagnosis*
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Humans
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Leishmaniasis / diagnosis
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Lymphadenitis / diagnosis*
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Lymphadenitis / parasitology
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Lymphadenitis / pathology
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Polymerase Chain Reaction*
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RNA, Protozoan / genetics
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RNA, Ribosomal, 18S / genetics
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Toxoplasma / genetics
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Toxoplasma / isolation & purification
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Toxoplasmosis / diagnosis*
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Toxoplasmosis / parasitology
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Toxoplasmosis / pathology
Substances
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DNA, Protozoan
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DNA, Ribosomal
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RNA, Protozoan
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RNA, Ribosomal, 18S