Biology of thrombopoietin

Curr Opin Pediatr. 1998 Feb;10(1):60-4. doi: 10.1097/00008480-199802000-00012.

Abstract

Thrombopoietin is a hematopoietic growth factor that stimulates megakaryopoiesis. Recent results indicate that thrombopoietin has multilineage hematopoietic effects both in vitro and in vivo. Clinical studies of thrombopoietin have begun, and are reviewed.

Publication types

  • Review

MeSH terms

  • Animals
  • Blood Platelets / physiology
  • Hematopoiesis / physiology
  • Humans
  • Liver / physiology
  • Randomized Controlled Trials as Topic
  • Recombinant Proteins
  • Thrombopoietin / physiology*
  • Thrombopoietin / therapeutic use

Substances

  • Recombinant Proteins
  • Thrombopoietin