Tongue cancer treated with brachytherapy: is thickness of tongue cancer a prognostic factor for regional control?

Anticancer Res. 1998 Mar-Apr;18(2B):1261-5.

Abstract

Background: We aimed to investigate the predisposing factor for lymph node metastasis and examine the influence of thickness for lymph node recurrence in oral tongue cancer.

Methods: We analysed 254 patients with early oral tongue cancer (T1-2N0) who were treated with brachytherapy from 1967 through 1985.

Results: T category (p = 0.005), and thickness (p = 0.04) were identified as a significant predisposing factors for neck failure. 50%, 40% and 30% were the incidences of lymph node metastasis for patients with thickness of tumor more than 11 mm, 6-10 mm and 5 mm or less. Furthermore, T category (largest diameter of lesion) correlates strongly to thickness of tumor.

Conclusions: Although it is not an independent factor, thickness is a significant predisposing factor for lymph node metastasis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Brachytherapy*
  • Female
  • Follow-Up Studies
  • Humans
  • Lymphatic Metastasis
  • Male
  • Middle Aged
  • Prognosis
  • Tongue Neoplasms / pathology
  • Tongue Neoplasms / radiotherapy*