Abstract
It is now possible to design small proteins capable of folding into compact structures with well-packed cores. Given the present state of knowledge of protein folding and design, it is possible to extract a set of engineering guidelines that may assist in future de novo protein design.
Publication types
-
Research Support, Non-U.S. Gov't
-
Research Support, U.S. Gov't, P.H.S.
-
Review
MeSH terms
-
Protein Conformation
-
Protein Engineering / methods*
-
Protein Engineering / trends
-
Protein Folding*
-
Proteins / chemistry*
-
Proteins / metabolism
-
Recombinant Proteins / chemistry
-
Recombinant Proteins / metabolism
Substances
-
Proteins
-
Recombinant Proteins