Cellular mechanisms of aquaporin trafficking

Am J Physiol. 1998 Sep;275(3):F328-31. doi: 10.1152/ajprenal.1998.275.3.F328.

Abstract

Aquaporins (AQPs) are a family of functionally important water channel proteins that are of special cell biological interest because of their diverse intracellular targeting and trafficking properties. AQPs have been found in many different cells and tissues. This short review summarizes recent work that addresses the regulation of AQP2 trafficking in response to vasopressin.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Aquaporin 2
  • Aquaporin 6
  • Aquaporins*
  • Cyclic AMP-Dependent Protein Kinases / metabolism
  • Cytoskeleton
  • Homeostasis
  • Humans
  • Ion Channels / metabolism*
  • Kidney Tubules / metabolism
  • Phosphorylation
  • Vasopressins / pharmacology

Substances

  • AQP2 protein, human
  • Aquaporin 2
  • Aquaporin 6
  • Aquaporins
  • Ion Channels
  • Vasopressins
  • Cyclic AMP-Dependent Protein Kinases