Glycopeptide-induced vasculitis--cross-reactivity between vancomycin and teicoplanin

J Infect. 1998 Jul;37(1):82-3. doi: 10.1016/s0163-4453(98)91077-5.

Abstract

Teicoplanin has been suggested for use in patients suffering complications from vancomycin. We describe two patients who developed a vasculitic rash whilst on vancomycin with recrudescence of the rash with subsequent teicoplanin therapy.

Publication types

  • Case Reports

MeSH terms

  • Anti-Bacterial Agents / adverse effects*
  • Anti-Bacterial Agents / therapeutic use
  • Bacteremia / drug therapy*
  • Bacteremia / microbiology
  • Cross Reactions
  • Drug Hypersensitivity
  • Humans
  • Male
  • Methicillin Resistance
  • Middle Aged
  • Staphylococcal Infections / drug therapy*
  • Staphylococcus aureus*
  • Teicoplanin / adverse effects*
  • Teicoplanin / therapeutic use
  • Vancomycin / adverse effects*
  • Vancomycin / therapeutic use
  • Vasculitis / chemically induced*
  • Wound Infection / microbiology

Substances

  • Anti-Bacterial Agents
  • Teicoplanin
  • Vancomycin