Objective evaluation of Papanicolaou staining

Anal Quant Cytol Histol. 1998 Aug;20(4):250-6.

Abstract

Objective: To evaluate the color of cytoplasm stained by Papanicolaou staining quantitatively.

Study design: Cytoplasm photographed under the same conditions was measured for spectral reflection by colorimetry, and the color of the cytoplasm was shown by the L*a*b* color specification.

Results: This method enabled us to specify the color of cytoplasm, which was classified in light green, eosin and orangeophilic.

Conclusion: The variation in the color of cytoplasm by different staining methods was quantified and related to the dyes absorbed by the cytoplasm.

MeSH terms

  • Colorimetry
  • Cytoplasm / chemistry
  • Epithelial Cells / chemistry
  • Female
  • Histocytochemistry
  • Humans
  • Mouth / cytology
  • Papanicolaou Test*
  • Sputum / cytology
  • Staining and Labeling / methods*
  • Vaginal Smears / methods*