Abstract
A Thoroughbred-Quarter Horse crossbred foal developed hemorrhagic enteritis and died < 48 hours after birth. Gross and histologic findings were suggestive of Clostridium perfringens type C infection, and large numbers of C perfringens were isolated from intestinal contents. However, genotyping of isolates indicated that they were enterotoxigenic C perfringens type A, and isolates were found to produce C perfringens enterotoxin in vitro. This case suggests that enterotoxigenic C perfringens type A may cause enteric disease in horses.
Publication types
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Case Reports
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Animals
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Animals, Newborn
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Blotting, Western / veterinary
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Clostridium Infections / microbiology
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Clostridium Infections / pathology
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Clostridium Infections / veterinary*
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Clostridium perfringens / classification*
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Clostridium perfringens / genetics
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Clostridium perfringens / metabolism
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Enteritis / microbiology
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Enteritis / pathology
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Enteritis / veterinary*
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Enterotoxins / analysis
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Enterotoxins / biosynthesis*
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Enterotoxins / genetics
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Genotype
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Horse Diseases / microbiology*
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Horse Diseases / pathology
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Horses
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Intestines / chemistry
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Intestines / microbiology
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Intestines / pathology
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Necrosis
Substances
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Enterotoxins
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enterotoxin, Clostridium