Abstract
Chemical studies of the coprophilous fungus Ascodesmis sphaerospora (JS 247) have led to the isolation of arugosin F (1), a new antifungal and antibacterial metabolite. The structure was determined based on NMR and MS data and on comparison with data for known members of the arugosin class. A known xanthone (2) was also isolated.
Publication types
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Antifungal Agents / isolation & purification
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Antifungal Agents / pharmacology*
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Ascomycota / chemistry*
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Benzoxepins / isolation & purification
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Benzoxepins / pharmacology*
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Magnetic Resonance Spectroscopy
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Mass Spectrometry
Substances
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Antifungal Agents
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Benzoxepins
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arugosin F