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Transgenic mice overexpressing truncated trkB neurotrophin receptors in neurons show increased susceptibility to cortical injury after focal cerebral ischemia.
Saarelainen T, Lukkarinen JA, Koponen S, Gröhn OH, Jolkkonen J, Koponen E, Haapasalo A, Alhonen L, Wong G, Koistinaho J, Kauppinen RA, Castrén E. Saarelainen T, et al. Among authors: haapasalo a. Mol Cell Neurosci. 2000 Aug;16(2):87-96. doi: 10.1006/mcne.2000.0863. Mol Cell Neurosci. 2000. PMID: 10924253
Activation of the TrkB neurotrophin receptor is induced by antidepressant drugs and is required for antidepressant-induced behavioral effects.
Saarelainen T, Hendolin P, Lucas G, Koponen E, Sairanen M, MacDonald E, Agerman K, Haapasalo A, Nawa H, Aloyz R, Ernfors P, Castrén E. Saarelainen T, et al. Among authors: haapasalo a. J Neurosci. 2003 Jan 1;23(1):349-57. doi: 10.1523/JNEUROSCI.23-01-00349.2003. J Neurosci. 2003. PMID: 12514234 Free PMC article.
A small TAT-TrkB peptide prevents BDNF receptor cleavage and restores synaptic physiology in Alzheimer's disease.
Fonseca-Gomes J, Costa-Coelho T, Ferreira-Manso M, Inteiro-Oliveira S, Vaz SH, Alemãn-Serrano N, Atalaia-Barbacena H, Ribeiro-Rodrigues L, Ramalho RM, Pinto R, Vicente Miranda H, Tanqueiro SR, de Almeida-Borlido C, Ramalho MJ, Miranda-Lourenço C, Belo RF, Ferreira CB, Neves V, Rombo DM, Viais R, Martins IC, Jerónimo-Santos A, Caetano A, Manso N, Mäkinen P, Marttinen M, Takalo M, Bremang M, Pike I, Haapasalo A, Loureiro JA, Pereira MC, Santos NC, Outeiro TF, Castanho MARB, Fernandes A, Hiltunen M, Duarte CB, Castrén E, de Mendonça A, Sebastião AM, Rodrigues TM, Diógenes MJ. Fonseca-Gomes J, et al. Among authors: haapasalo a. Mol Ther. 2024 Oct 2;32(10):3372-3401. doi: 10.1016/j.ymthe.2024.08.022. Epub 2024 Aug 27. Mol Ther. 2024. PMID: 39205389 Free article.
124 results