Schuetz JD - Search Results

1

Reduced folate carrier expression in acute lymphoblastic leukemia: a mechanism for ploidy but not lineage differences in methotrexate accumulation.

Belkov VM, Krynetski EY, Schuetz JD, Yanishevski Y, Masson E, Mathew S, Raimondi S, Pui CH, Relling MV, Evans WE. Belkov VM, et al. Among authors: schuetz jd. Blood. 1999 Mar 1;93(5):1643-50. Blood. 1999. PMID: 10029593 Free article. Clinical Trial.

2

Accumulation of methotrexate polyglutamates in lymphoblasts is a determinant of antileukemic effects in vivo. A rationale for high-dose methotrexate.

Masson E, Relling MV, Synold TW, Liu Q, Schuetz JD, Sandlund JT, Pui CH, Evans WE. Masson E, et al. Among authors: schuetz jd. J Clin Invest. 1996 Jan 1;97(1):73-80. doi: 10.1172/JCI118409. J Clin Invest. 1996. PMID: 8550853 Free PMC article. Clinical Trial.

3

Allopurinol inhibits de novo purine synthesis in lymphoblasts of children with acute lymphoblastic leukemia.

Masson E, Synold TW, Relling MV, Schuetz JD, Sandlund JT, Pui CH, Evans WE. Masson E, et al. Among authors: schuetz jd. Leukemia. 1996 Jan;10(1):56-60. Leukemia. 1996. PMID: 8558939 Clinical Trial.

4

Differences in folylpolyglutamate synthetase and dihydrofolate reductase expression in human B-lineage versus T-lineage leukemic lymphoblasts: mechanisms for lineage differences in methotrexate polyglutamylation and cytotoxicity.

Galpin AJ, Schuetz JD, Masson E, Yanishevski Y, Synold TW, Barredo JC, Pui CH, Relling MV, Evans WE. Galpin AJ, et al. Among authors: schuetz jd. Mol Pharmacol. 1997 Jul;52(1):155-63. doi: 10.1124/mol.52.1.155. Mol Pharmacol. 1997. PMID: 9224825

5

A single point mutation leading to loss of catalytic activity in human thiopurine S-methyltransferase.

Krynetski EY, Schuetz JD, Galpin AJ, Pui CH, Relling MV, Evans WE. Krynetski EY, et al. Among authors: schuetz jd. Proc Natl Acad Sci U S A. 1995 Feb 14;92(4):949-53. doi: 10.1073/pnas.92.4.949. Proc Natl Acad Sci U S A. 1995. PMID: 7862671 Free PMC article.

6

Genetic polymorphism of thiopurine S-methyltransferase: clinical importance and molecular mechanisms.

Krynetski EY, Tai HL, Yates CR, Fessing MY, Loennechen T, Schuetz JD, Relling MV, Evans WE. Krynetski EY, et al. Among authors: schuetz jd. Pharmacogenetics. 1996 Aug;6(4):279-90. doi: 10.1097/00008571-199608000-00001. Pharmacogenetics. 1996. PMID: 8873214 Review.

7

Promoter and intronic sequences of the human thiopurine S-methyltransferase (TPMT) gene isolated from a human PAC1 genomic library.

Krynetski EY, Fessing MY, Yates CR, Sun D, Schuetz JD, Evans WE. Krynetski EY, et al. Among authors: schuetz jd. Pharm Res. 1997 Dec;14(12):1672-8. doi: 10.1023/a:1012111325397. Pharm Res. 1997. PMID: 9453052

8

Structural and functional analysis of the human TPMT gene promoter.

Fessing MY, Krynetski EY, Schuetz JD, Evans WE. Fessing MY, et al. Among authors: schuetz jd. Adv Exp Med Biol. 1998;431:315-8. doi: 10.1007/978-1-4615-5381-6_62. Adv Exp Med Biol. 1998. PMID: 9598082 No abstract available.

9

Differential effects of thiopurine methyltransferase (TPMT) and multidrug resistance-associated protein gene 4 (MRP4) on mercaptopurine toxicity.

Liu C, Janke LJ, Yang JJ, Evans WE, Schuetz JD, Relling MV. Liu C, et al. Among authors: schuetz jd. Cancer Chemother Pharmacol. 2017 Aug;80(2):287-293. doi: 10.1007/s00280-017-3361-2. Epub 2017 Jun 16. Cancer Chemother Pharmacol. 2017. PMID: 28623449 Free PMC article.

10

P-glycoprotein: a major determinant of rifampicin-inducible expression of cytochrome P4503A in mice and humans.

Schuetz EG, Schinkel AH, Relling MV, Schuetz JD. Schuetz EG, et al. Among authors: schuetz jd. Proc Natl Acad Sci U S A. 1996 Apr 30;93(9):4001-5. doi: 10.1073/pnas.93.9.4001. Proc Natl Acad Sci U S A. 1996. PMID: 8633005 Free PMC article.

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