Kawano Y - Search Results

1

CD44 cleavage induced by a membrane-associated metalloprotease plays a critical role in tumor cell migration.

Okamoto I, Kawano Y, Tsuiki H, Sasaki J, Nakao M, Matsumoto M, Suga M, Ando M, Nakajima M, Saya H. Okamoto I, et al. Among authors: kawano y. Oncogene. 1999 Feb 18;18(7):1435-46. doi: 10.1038/sj.onc.1202447. Oncogene. 1999. PMID: 10050880

2

Presenilin-dependent gamma-secretase activity mediates the intramembranous cleavage of CD44.

Murakami D, Okamoto I, Nagano O, Kawano Y, Tomita T, Iwatsubo T, De Strooper B, Yumoto E, Saya H. Murakami D, et al. Among authors: kawano y. Oncogene. 2003 Mar 13;22(10):1511-6. doi: 10.1038/sj.onc.1206298. Oncogene. 2003. PMID: 12629514

3

Regulated CD44 cleavage under the control of protein kinase C, calcium influx, and the Rho family of small G proteins.

Okamoto I, Kawano Y, Matsumoto M, Suga M, Kaibuchi K, Ando M, Saya H. Okamoto I, et al. Among authors: kawano y. J Biol Chem. 1999 Sep 3;274(36):25525-34. doi: 10.1074/jbc.274.36.25525. J Biol Chem. 1999. PMID: 10464284 Free article.

Our previous studies have shown that CD44 expressed in cancer cells is proteolytically cleaved at the extracellular domain through membrane-associated metalloproteases and that CD44 cleavage plays a critical role in CD44-mediated tumor cell migration (Okamoto, I., Kawano, …

Our previous studies have shown that CD44 expressed in cancer cells is proteolytically cleaved at the extracellular domain through membrane- …

4

Calcium influx triggers the sequential proteolysis of extracellular and cytoplasmic domains of E-cadherin, leading to loss of beta-catenin from cell-cell contacts.

Ito K, Okamoto I, Araki N, Kawano Y, Nakao M, Fujiyama S, Tomita K, Mimori T, Saya H. Ito K, et al. Among authors: kawano y. Oncogene. 1999 Nov 25;18(50):7080-90. doi: 10.1038/sj.onc.1203191. Oncogene. 1999. PMID: 10597309

5

Ras oncoprotein induces CD44 cleavage through phosphoinositide 3-OH kinase and the rho family of small G proteins.

Kawano Y, Okamoto I, Murakami D, Itoh H, Yoshida M, Ueda S, Saya H. Kawano Y, et al. J Biol Chem. 2000 Sep 22;275(38):29628-35. doi: 10.1074/jbc.M002440200. J Biol Chem. 2000. PMID: 10896935 Free article.

6

Proteolytic release of CD44 intracellular domain and its role in the CD44 signaling pathway.

Okamoto I, Kawano Y, Murakami D, Sasayama T, Araki N, Miki T, Wong AJ, Saya H. Okamoto I, et al. Among authors: kawano y. J Cell Biol. 2001 Nov 26;155(5):755-62. doi: 10.1083/jcb.200108159. Epub 2001 Nov 19. J Cell Biol. 2001. PMID: 11714729 Free PMC article.

7

Multiple roles of vertebrate REV genes in DNA repair and recombination.

Okada T, Sonoda E, Yoshimura M, Kawano Y, Saya H, Kohzaki M, Takeda S. Okada T, et al. Among authors: kawano y. Mol Cell Biol. 2005 Jul;25(14):6103-11. doi: 10.1128/MCB.25.14.6103-6111.2005. Mol Cell Biol. 2005. PMID: 15988022 Free PMC article.

8

Phosphorylation of adducin by Rho-kinase plays a crucial role in cell motility.

Fukata Y, Oshiro N, Kinoshita N, Kawano Y, Matsuoka Y, Bennett V, Matsuura Y, Kaibuchi K. Fukata Y, et al. Among authors: kawano y. J Cell Biol. 1999 Apr 19;145(2):347-61. doi: 10.1083/jcb.145.2.347. J Cell Biol. 1999. PMID: 10209029 Free PMC article.

9

Phosphorylation of myosin-binding subunit (MBS) of myosin phosphatase by Rho-kinase in vivo.

Kawano Y, Fukata Y, Oshiro N, Amano M, Nakamura T, Ito M, Matsumura F, Inagaki M, Kaibuchi K. Kawano Y, et al. J Cell Biol. 1999 Nov 29;147(5):1023-38. doi: 10.1083/jcb.147.5.1023. J Cell Biol. 1999. PMID: 10579722 Free PMC article.

10

Inhibition of myosin phosphatase by upregulated rho-kinase plays a key role for coronary artery spasm in a porcine model with interleukin-1beta.

Kandabashi T, Shimokawa H, Miyata K, Kunihiro I, Kawano Y, Fukata Y, Higo T, Egashira K, Takahashi S, Kaibuchi K, Takeshita A. Kandabashi T, et al. Among authors: kawano y. Circulation. 2000 Mar 21;101(11):1319-23. doi: 10.1161/01.cir.101.11.1319. Circulation. 2000. PMID: 10725293

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