MacLaren DC - Search Results

1

Imaging adenoviral-directed reporter gene expression in living animals with positron emission tomography.

Gambhir SS, Barrio JR, Phelps ME, Iyer M, Namavari M, Satyamurthy N, Wu L, Green LA, Bauer E, MacLaren DC, Nguyen K, Berk AJ, Cherry SR, Herschman HR. Gambhir SS, et al. Among authors: maclaren dc. Proc Natl Acad Sci U S A. 1999 Mar 2;96(5):2333-8. doi: 10.1073/pnas.96.5.2333. Proc Natl Acad Sci U S A. 1999. PMID: 10051642 Free PMC article.

2

Imaging of adenoviral-directed herpes simplex virus type 1 thymidine kinase reporter gene expression in mice with radiolabeled ganciclovir.

Gambhir SS, Barrio JR, Wu L, Iyer M, Namavari M, Satyamurthy N, Bauer E, Parrish C, MacLaren DC, Borghei AR, Green LA, Sharfstein S, Berk AJ, Cherry SR, Phelps ME, Herschman HR. Gambhir SS, et al. Among authors: maclaren dc. J Nucl Med. 1998 Nov;39(11):2003-11. J Nucl Med. 1998. PMID: 9829598 Free article.

3

Repetitive, non-invasive imaging of the dopamine D2 receptor as a reporter gene in living animals.

MacLaren DC, Gambhir SS, Satyamurthy N, Barrio JR, Sharfstein S, Toyokuni T, Wu L, Berk AJ, Cherry SR, Phelps ME, Herschman HR. MacLaren DC, et al. Gene Ther. 1999 May;6(5):785-91. doi: 10.1038/sj.gt.3300877. Gene Ther. 1999. PMID: 10505102

4

Seeing is believing: non-invasive, quantitative and repetitive imaging of reporter gene expression in living animals, using positron emission tomography.

Herschman HR, MacLaren DC, Iyer M, Namavari M, Bobinski K, Green LA, Wu L, Berk AJ, Toyokuni T, Barrio JR, Cherry SR, Phelps ME, Sandgren EP, Gambhir SS. Herschman HR, et al. Among authors: maclaren dc. J Neurosci Res. 2000 Mar 15;59(6):699-705. doi: 10.1002/(SICI)1097-4547(20000315)59:6<699::AID-JNR1>3.0.CO;2-1. J Neurosci Res. 2000. PMID: 10700006 Review.

5

PET imaging of transgene expression.

MacLaren DC, Toyokuni T, Cherry SR, Barrio JR, Phelps ME, Herschman HR, Gambhir SS. MacLaren DC, et al. Biol Psychiatry. 2000 Sep 1;48(5):337-48. doi: 10.1016/s0006-3223(00)00970-7. Biol Psychiatry. 2000. PMID: 10978717 Review.

6

Deficiency of a protein-repair enzyme results in the accumulation of altered proteins, retardation of growth, and fatal seizures in mice.

Kim E, Lowenson JD, MacLaren DC, Clarke S, Young SG. Kim E, et al. Among authors: maclaren dc. Proc Natl Acad Sci U S A. 1997 Jun 10;94(12):6132-7. doi: 10.1073/pnas.94.12.6132. Proc Natl Acad Sci U S A. 1997. PMID: 9177182 Free PMC article.

7

The L-isoaspartyl/D-aspartyl protein methyltransferase gene (PCMT1) maps to human chromosome 6q22.3-6q24 and the syntenic region of mouse chromosome 10.

MacLaren DC, O'Connor CM, Xia YR, Mehrabian M, Klisak I, Sparkes RS, Clarke S, Lusis AJ. MacLaren DC, et al. Genomics. 1992 Dec;14(4):852-6. doi: 10.1016/s0888-7543(05)80104-1. Genomics. 1992. PMID: 1478665

8

Crystal structure of human L-isoaspartyl methyltransferase.

Ryttersgaard C, Griffith SC, Sawaya MR, MacLaren DC, Clarke S, Yeates TO. Ryttersgaard C, et al. Among authors: maclaren dc. J Biol Chem. 2002 Mar 22;277(12):10642-6. doi: 10.1074/jbc.M200229200. Epub 2002 Jan 15. J Biol Chem. 2002. PMID: 11792715 Free article.

9

Expression and purification of a human recombinant methyltransferase that repairs damaged proteins.

MacLaren DC, Clarke S. MacLaren DC, et al. Protein Expr Purif. 1995 Feb;6(1):99-108. doi: 10.1006/prep.1995.1013. Protein Expr Purif. 1995. PMID: 7756844

10

Alternative splicing of the human isoaspartyl protein carboxyl methyltransferase RNA leads to the generation of a C-terminal -RDEL sequence in isozyme II.

MacLaren DC, Kagan RM, Clarke S. MacLaren DC, et al. Biochem Biophys Res Commun. 1992 May 29;185(1):277-83. doi: 10.1016/s0006-291x(05)80987-8. Biochem Biophys Res Commun. 1992. PMID: 1339271

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