La Colla P - Search Results

1

5-Alkyl-2-(alkylthio)-6-(2,6-dihalophenylmethyl)-3, 4-dihydropyrimidin-4(3H)-ones: novel potent and selective dihydro-alkoxy-benzyl-oxopyrimidine derivatives.

Mai A, Artico M, Sbardella G, Massa S, Novellino E, Greco G, Loi AG, Tramontano E, Marongiu ME, La Colla P. Mai A, et al. Among authors: la colla p. J Med Chem. 1999 Feb 25;42(4):619-27. doi: 10.1021/jm980260f. J Med Chem. 1999. PMID: 10052969

2

Synthesis, biological evaluation, and binding mode of novel 1-[2-(diarylmethoxy)ethyl]-2-methyl-5-nitroimidazoles targeted at the HIV-1 reverse transcriptase.

Silvestri R, Artico M, De Martino G, Ragno R, Massa S, Loddo R, Murgioni C, Loi AG, La Colla P, Pani A. Silvestri R, et al. Among authors: la colla p. J Med Chem. 2002 Apr 11;45(8):1567-76. doi: 10.1021/jm010904a. J Med Chem. 2002. PMID: 11931611

3

Design, synthesis and QSAR studies on N-aryl heteroarylisopropanolamines, a new class of non-peptidic HIV-1 protease inhibitors.

Di Santo R, Costi R, Artico M, Massa S, Ragno R, Marshall GR, La Colla P. Di Santo R, et al. Among authors: la colla p. Bioorg Med Chem. 2002 Aug;10(8):2511-26. doi: 10.1016/s0968-0896(02)00119-0. Bioorg Med Chem. 2002. PMID: 12057640

4

Novel indolyl aryl sulfones active against HIV-1 carrying NNRTI resistance mutations: synthesis and SAR studies.

Silvestri R, De Martino G, La Regina G, Artico M, Massa S, Vargiu L, Mura M, Loi AG, Marceddu T, La Colla P. Silvestri R, et al. Among authors: la regina g, la colla p. J Med Chem. 2003 Jun 5;46(12):2482-93. doi: 10.1021/jm0211063. J Med Chem. 2003. PMID: 12773052

5

2,6-Bis(3,4,5-trihydroxybenzylydene) derivatives of cyclohexanone: novel potent HIV-1 integrase inhibitors that prevent HIV-1 multiplication in cell-based assays.

Costi R, Santo RD, Artico M, Massa S, Ragno R, Loddo R, La Colla M, Tramontano E, La Colla P, Pani A. Costi R, et al. Among authors: la colla m, la colla p. Bioorg Med Chem. 2004 Jan 2;12(1):199-215. doi: 10.1016/j.bmc.2003.10.005. Bioorg Med Chem. 2004. PMID: 14697785

6

Computer-aided design, synthesis, and anti-HIV-1 activity in vitro of 2-alkylamino-6-[1-(2,6-difluorophenyl)alkyl]-3,4-dihydro-5-alkylpyrimidin-4(3H)-ones as novel potent non-nucleoside reverse transcriptase inhibitors, also active against the Y181C variant.

Ragno R, Mai A, Sbardella G, Artico M, Massa S, Musiu C, Mura M, Marturana F, Cadeddu A, La Colla P. Ragno R, et al. Among authors: la colla p. J Med Chem. 2004 Feb 12;47(4):928-34. doi: 10.1021/jm0309856. J Med Chem. 2004. PMID: 14761194

7

Synthesis and in vitro antimycobacterial activity of novel 3-(1H-pyrrol-1-yl)-2-oxazolidinone analogues of PNU-100480.

Sbardella G, Mai A, Artico M, Loddo R, Setzu MG, La Colla P. Sbardella G, et al. Among authors: la colla p. Bioorg Med Chem Lett. 2004 Mar 22;14(6):1537-41. doi: 10.1016/j.bmcl.2004.01.010. Bioorg Med Chem Lett. 2004. PMID: 15006398

8

6-aryl-2,4-dioxo-5-hexenoic acids, novel integrase inhibitors active against HIV-1 multiplication in cell-based assays.

Costi R, Di Santo R, Artico M, Roux A, Ragno R, Massa S, Tramontano E, La Colla M, Loddo R, Marongiu ME, Pani A, La Colla P. Costi R, et al. Among authors: la colla m, la colla p. Bioorg Med Chem Lett. 2004 Apr 5;14(7):1745-9. doi: 10.1016/j.bmcl.2004.01.037. Bioorg Med Chem Lett. 2004. PMID: 15026063

9

Simple, short peptide derivatives of a sulfonylindolecarboxamide (L-737,126) active in vitro against HIV-1 wild type and variants carrying non-nucleoside reverse transcriptase inhibitor resistance mutations.

Silvestri R, Artico M, De Martino G, La Regina G, Loddo R, La Colla M, Mura M, La Colla P. Silvestri R, et al. Among authors: la colla m, la regina g, la colla p. J Med Chem. 2004 Jul 15;47(15):3892-6. doi: 10.1021/jm031147e. J Med Chem. 2004. PMID: 15239667

10

5-Alkyl-2-alkylamino-6-(2,6-difluorophenylalkyl)-3,4-dihydropyrimidin-4(3H)-ones, a new series of potent, broad-spectrum non-nucleoside reverse transcriptase inhibitors belonging to the DABO family.

Mai A, Artico M, Ragno R, Sbardella G, Massa S, Musiu C, Mura M, Marturana F, Cadeddu A, Maga G, La Colla P. Mai A, et al. Among authors: la colla p. Bioorg Med Chem. 2005 Mar 15;13(6):2065-77. doi: 10.1016/j.bmc.2005.01.005. Bioorg Med Chem. 2005. PMID: 15727860

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