Mansfield SG - Search Results

1

Spliceosome-mediated RNA trans-splicing as a tool for gene therapy.

Puttaraju M, Jamison SF, Mansfield SG, Garcia-Blanco MA, Mitchell LG. Puttaraju M, et al. Among authors: mansfield sg. Nat Biotechnol. 1999 Mar;17(3):246-52. doi: 10.1038/6986. Nat Biotechnol. 1999. PMID: 10096291

2

Partial correction of endogenous DeltaF508 CFTR in human cystic fibrosis airway epithelia by spliceosome-mediated RNA trans-splicing.

Liu X, Jiang Q, Mansfield SG, Puttaraju M, Zhang Y, Zhou W, Cohn JA, Garcia-Blanco MA, Mitchell LG, Engelhardt JF. Liu X, et al. Among authors: mansfield sg. Nat Biotechnol. 2002 Jan;20(1):47-52. doi: 10.1038/nbt0102-47. Nat Biotechnol. 2002. PMID: 11753361

3

Phenotype correction of hemophilia A mice by spliceosome-mediated RNA trans-splicing.

Chao H, Mansfield SG, Bartel RC, Hiriyanna S, Mitchell LG, Garcia-Blanco MA, Walsh CE. Chao H, et al. Among authors: mansfield sg. Nat Med. 2003 Aug;9(8):1015-9. doi: 10.1038/nm900. Epub 2003 Jul 6. Nat Med. 2003. PMID: 12847523

4

5' exon replacement and repair by spliceosome-mediated RNA trans-splicing.

Mansfield SG, Clark RH, Puttaraju M, Kole J, Cohn JA, Mitchell LG, Garcia-Blanco MA. Mansfield SG, et al. RNA. 2003 Oct;9(10):1290-7. doi: 10.1261/rna.5101903. RNA. 2003. PMID: 13130143 Free PMC article.

5

Repair of CFTR mRNA by spliceosome-mediated RNA trans-splicing.

Mansfield SG, Kole J, Puttaraju M, Yang CC, Garcia-Blanco MA, Cohn JA, Mitchell LG. Mansfield SG, et al. Gene Ther. 2000 Nov;7(22):1885-95. doi: 10.1038/sj.gt.3301307. Gene Ther. 2000. PMID: 11127576

6

Trans-splicing into highly abundant albumin transcripts for production of therapeutic proteins in vivo.

Wang J, Mansfield SG, Cote CA, Jiang PD, Weng K, Amar MJ, Brewer BH Jr, Remaley AT, McGarrity GJ, Garcia-Blanco MA, Puttaraju M. Wang J, et al. Among authors: mansfield sg. Mol Ther. 2009 Feb;17(2):343-51. doi: 10.1038/mt.2008.260. Epub 2008 Dec 9. Mol Ther. 2009. PMID: 19066600 Free PMC article.

7

Spliceosome-mediated RNA trans-splicing with recombinant adeno-associated virus partially restores cystic fibrosis transmembrane conductance regulator function to polarized human cystic fibrosis airway epithelial cells.

Liu X, Luo M, Zhang LN, Yan Z, Zak R, Ding W, Mansfield SG, Mitchell LG, Engelhardt JF. Liu X, et al. Among authors: mansfield sg. Hum Gene Ther. 2005 Sep;16(9):1116-23. doi: 10.1089/hum.2005.16.1116. Hum Gene Ther. 2005. PMID: 16149910

8

Reprogramming of tau alternative splicing by spliceosome-mediated RNA trans-splicing: implications for tauopathies.

Rodriguez-Martin T, Garcia-Blanco MA, Mansfield SG, Grover AC, Hutton M, Yu Q, Zhou J, Anderton BH, Gallo JM. Rodriguez-Martin T, et al. Among authors: mansfield sg. Proc Natl Acad Sci U S A. 2005 Oct 25;102(43):15659-64. doi: 10.1073/pnas.0503150102. Epub 2005 Oct 17. Proc Natl Acad Sci U S A. 2005. PMID: 16230627 Free PMC article.

9

Correction of tau mis-splicing caused by FTDP-17 MAPT mutations by spliceosome-mediated RNA trans-splicing.

Rodriguez-Martin T, Anthony K, Garcia-Blanco MA, Mansfield SG, Anderton BH, Gallo JM. Rodriguez-Martin T, et al. Among authors: mansfield sg. Hum Mol Genet. 2009 Sep 1;18(17):3266-73. doi: 10.1093/hmg/ddp264. Epub 2009 Jun 4. Hum Mol Genet. 2009. PMID: 19498037 Free PMC article.

10

RNA repair using spliceosome-mediated RNA trans-splicing.

Mansfield SG, Chao H, Walsh CE. Mansfield SG, et al. Trends Mol Med. 2004 Jun;10(6):263-8. doi: 10.1016/j.molmed.2004.04.007. Trends Mol Med. 2004. PMID: 15177190 Review. No abstract available.

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