Young SG - Search Results

1

A new approach for studying gene regulation by distant DNA elements in transgenic mice.

Nielsen LB, McCormick SP, Young SG. Nielsen LB, et al. Among authors: young sg. Scand J Clin Lab Invest Suppl. 1999;229:33-9. doi: 10.1080/00365519950185931. Scand J Clin Lab Invest Suppl. 1999. PMID: 10097288 Review.

2

Human apolipoprotein B transgenic mice generated with 207- and 145-kilobase pair bacterial artificial chromosomes. Evidence that a distant 5'-element confers appropriate transgene expression in the intestine.

Nielsen LB, McCormick SP, Pierotti V, Tam C, Gunn MD, Shizuya H, Young SG. Nielsen LB, et al. Among authors: young sg. J Biol Chem. 1997 Nov 21;272(47):29752-8. doi: 10.1074/jbc.272.47.29752. J Biol Chem. 1997. PMID: 9368045 Free article.

3

Expression of P1 DNA in mammalian cells and transgenic mice.

McCormick SP, Linton MF, Young SG. McCormick SP, et al. Among authors: young sg. Genet Anal Tech Appl. 1994;11(5-6):158-64. doi: 10.1016/1050-3862(94)90036-1. Genet Anal Tech Appl. 1994. PMID: 7710781

4

Expression of human apolipoprotein B90 in transgenic mice. Demonstration that apolipoprotein B90 lacks the structural requirements to form lipoprotein.

McCormick SP, Linton MF, Hobbs HH, Taylor S, Curtiss LK, Young SG. McCormick SP, et al. Among authors: young sg. J Biol Chem. 1994 Sep 30;269(39):24284-9. J Biol Chem. 1994. PMID: 7929084 Free article.

5

Transgenic mice that overexpress mouse apolipoprotein B. Evidence that the DNA sequences controlling intestinal expression of the apolipoprotein B gene are distant from the structural gene.

McCormick SP, Ng JK, Véniant M, Borén J, Pierotti V, Flynn LM, Grass DS, ConnollyA, Young SG. McCormick SP, et al. Among authors: young sg. J Biol Chem. 1996 May 17;271(20):11963-70. doi: 10.1074/jbc.271.20.11963. J Biol Chem. 1996. PMID: 8662599 Free article.

6

Construction of two near-kilobase resolution restriction maps of the 5' regulatory region of the human apolipoprotein B gene by quantitative DNA fiber mapping (QDFM).

Duell T, Nielsen LB, Jones A, Young SG, Weier HU. Duell T, et al. Among authors: young sg. Cytogenet Cell Genet. 1997;79(1-2):64-70. doi: 10.1159/000134685. Cytogenet Cell Genet. 1997. PMID: 9533015

7

Apolipoprotein B gene expression in a series of human apolipoprotein B transgenic mice generated with recA-assisted restriction endonuclease cleavage-modified bacterial artificial chromosomes. An intestine-specific enhancer element is located between 54 and 62 kilobases 5' to the structural gene.

Nielsen LB, Kahn D, Duell T, Weier HU, Taylor S, Young SG. Nielsen LB, et al. Among authors: young sg. J Biol Chem. 1998 Aug 21;273(34):21800-7. doi: 10.1074/jbc.273.34.21800. J Biol Chem. 1998. PMID: 9705318 Free article.

8

Insights into apolipoprotein B biology from transgenic and gene-targeted mice.

Véniant MM, Kim E, McCormick S, Borén J, Nielsen LB, Raabe M, Young SG. Véniant MM, et al. Among authors: young sg. J Nutr. 1999 Feb;129(2S Suppl):451S-455S. doi: 10.1093/jn/129.2.451S. J Nutr. 1999. PMID: 10064308 Review.

9

The DNA sequences required for apolipoprotein B expression in the heart are distinct from those required for expression in the intestine.

Nielsen LB, Sullivan M, Vanni-Reyes T, Goldberg IJ, Young SG. Nielsen LB, et al. Among authors: young sg. J Mol Cell Cardiol. 1999 Apr;31(4):695-703. doi: 10.1006/jmcc.1998.0918. J Mol Cell Cardiol. 1999. PMID: 10329198

10

Overexpression of human apolipoprotein B-100 in transgenic rabbits results in increased levels of LDL and decreased levels of HDL.

Fan J, McCormick SP, Krauss RM, Taylor S, Quan R, Taylor JM, Young SG. Fan J, et al. Among authors: young sg. Arterioscler Thromb Vasc Biol. 1995 Nov;15(11):1889-99. doi: 10.1161/01.atv.15.11.1889. Arterioscler Thromb Vasc Biol. 1995. PMID: 7583569

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