Direct detection of nucleic acid hybridization on the surface of a charge coupled device.
Lamture JB, Beattie KL, Burke BE, Eggers MD, Ehrlich DJ, Fowler R, Hollis MA, Kosicki BB, Reich RK, Smith SR, et al.
Lamture JB, et al. Among authors: eggers md.
Nucleic Acids Res. 1994 Jun 11;22(11):2121-5. doi: 10.1093/nar/22.11.2121.
Nucleic Acids Res. 1994.
PMID: 8029021
Free PMC article.
The salient feature of the method is that to achieve the highest possible collection efficiency, the hybridization matrix is placed directly on the surface of a charge coupled device (CCD), which is used to detect 32P decay from hybridized target molecules (1, Eggers, M …
The salient feature of the method is that to achieve the highest possible collection efficiency, the hybridization matrix is placed directly …