Sercel AD - Search Results

1

Synthesis, structure-activity relationships, and in vivo evaluations of substituted di-tert-butylphenols as a novel class of potent, selective, and orally active cyclooxygenase-2 inhibitors. 1. Thiazolone and oxazolone series.

Song Y, Connor DT, Doubleday R, Sorenson RJ, Sercel AD, Unangst PC, Roth BD, Gilbertsen RB, Chan K, Schrier DJ, Guglietta A, Bornemeier DA, Dyer RD. Song Y, et al. Among authors: sercel ad. J Med Chem. 1999 Apr 8;42(7):1151-60. doi: 10.1021/jm9805081. J Med Chem. 1999. PMID: 10197959

2

Synthesis, structure-activity relationships, and in vivo evaluations of substituted di-tert-butylphenols as a novel class of potent, selective, and orally active cyclooxygenase-2 inhibitors. 2. 1,3,4- and 1,2,4-thiadiazole series.

Song Y, Connor DT, Sercel AD, Sorenson RJ, Doubleday R, Unangst PC, Roth BD, Beylin VG, Gilbertsen RB, Chan K, Schrier DJ, Guglietta A, Bornemeier DA, Dyer RD. Song Y, et al. Among authors: sercel ad. J Med Chem. 1999 Apr 8;42(7):1161-9. doi: 10.1021/jm980570y. J Med Chem. 1999. PMID: 10197960

3

2,6-di-tert-butylphenols: a new class of potent and selective PGHS-2 inhibitor.

Song Y, Connor DT, Sorenson RJ, Doubleday R, Sercel AD, Unangst PC, Gilbertsen RB, Chan K, Bornemeier DA, Dyer RD. Song Y, et al. Among authors: sercel ad. Inflamm Res. 1997 Aug;46 Suppl 2:S141-2. doi: 10.1007/s000110050145. Inflamm Res. 1997. PMID: 9297551 No abstract available.

4

Tyrosine kinase inhibitors. 6. Structure-activity relationships among N- and 3-substituted 2,2'-diselenobis(1H-indoles) for inhibition of protein tyrosine kinases and comparative in vitro and in vivo studies against selected sulfur congeners.

Showalter HD, Sercel AD, Leja BM, Wolfangel CD, Ambroso LA, Elliott WL, Fry DW, Kraker AJ, Howard CT, Lu GH, Moore CW, Nelson JM, Roberts BJ, Vincent PW, Denny WA, Thompson AM. Showalter HD, et al. Among authors: sercel ad. J Med Chem. 1997 Feb 14;40(4):413-26. doi: 10.1021/jm960689b. J Med Chem. 1997. PMID: 9046331

5

Tyrosine kinase inhibitors. 16. 6,5,6-tricyclic benzothieno[3, 2-d]pyrimidines and pyrimido[5,4-b-] and -[4,5-b]ĭndoles as potent inhibitors of the epidermal growth factor receptor tyrosine kinase.

Showalter HD, Bridges AJ, Zhou H, Sercel AD, McMichael A, Fry DW. Showalter HD, et al. Among authors: sercel ad. J Med Chem. 1999 Dec 30;42(26):5464-74. doi: 10.1021/jm9903949. J Med Chem. 1999. PMID: 10639288

6

Anticancer activity in murine and human tumor cell lines of bis(platinum) complexes incorporating straight-chain aliphatic diamine linker groups.

Kraker AJ, Hoeschele JD, Elliott WL, Showalter HD, Sercel AD, Farrell NP. Kraker AJ, et al. Among authors: sercel ad. J Med Chem. 1992 Nov 27;35(24):4526-32. doi: 10.1021/jm00102a003. J Med Chem. 1992. PMID: 1335074

7

Benzothiopyranoindazoles, a new class of chromophore modified anthracenedione anticancer agents. Synthesis and activity against murine leukemias.

Showalter HD, Angelo MM, Berman EM, Kanter GD, Ortwine DF, Ross-Kesten SG, Sercel AD, Turner WR, Werbel LM, Worth DF, et al. Showalter HD, et al. Among authors: sercel ad. J Med Chem. 1988 Aug;31(8):1527-39. doi: 10.1021/jm00403a009. J Med Chem. 1988. PMID: 3397990

8

Tyrosine kinase inhibitors. 4. Structure-activity relationships among N- and 3-substituted 2,2'-dithiobis(1H-indoles) for in vitro inhibition of receptor and nonreceptor protein tyrosine kinases.

Palmer BD, Rewcastle GW, Thompson AM, Boyd M, Showalter HD, Sercel AD, Fry DW, Kraker AJ, Denny WA. Palmer BD, et al. Among authors: sercel ad. J Med Chem. 1995 Jan 6;38(1):58-67. doi: 10.1021/jm00001a011. J Med Chem. 1995. PMID: 7837241

9

Design and synthesis of 2-nitroimidazoles with variable alkylating and acylating functionality.

Winters T, Sercel A, Suto C, Elliott W, Leopold W, Leopold J, Showalter H. Winters T, et al. Chem Pharm Bull (Tokyo). 2014;62(3):301-3. doi: 10.1248/cpb.c13-00903. Chem Pharm Bull (Tokyo). 2014. PMID: 24583786 Free article.

10

Fluorous affinity purification of oligonucleotides.

Pearson WH, Berry DA, Stoy P, Jung KY, Sercel AD. Pearson WH, et al. Among authors: sercel ad. J Org Chem. 2005 Sep 2;70(18):7114-22. doi: 10.1021/jo050795y. J Org Chem. 2005. PMID: 16122230

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