Das S - Search Results

1

Phenotype-genotype correlation of in vitro SN-38 (active metabolite of irinotecan) and bilirubin glucuronidation in human liver tissue with UGT1A1 promoter polymorphism.

Iyer L, Hall D, Das S, Mortell MA, Ramírez J, Kim S, Di Rienzo A, Ratain MJ. Iyer L, et al. Among authors: das s. Clin Pharmacol Ther. 1999 May;65(5):576-82. doi: 10.1016/S0009-9236(99)70078-0. Clin Pharmacol Ther. 1999. PMID: 10340924

2

UGT1A1*28 polymorphism as a determinant of irinotecan disposition and toxicity.

Iyer L, Das S, Janisch L, Wen M, Ramírez J, Karrison T, Fleming GF, Vokes EE, Schilsky RL, Ratain MJ. Iyer L, et al. Among authors: das s. Pharmacogenomics J. 2002;2(1):43-7. doi: 10.1038/sj.tpj.6500072. Pharmacogenomics J. 2002. PMID: 11990381

3

Hepatocyte nuclear factor-1 alpha is associated with UGT1A1, UGT1A9 and UGT2B7 mRNA expression in human liver.

Ramírez J, Mirkov S, Zhang W, Chen P, Das S, Liu W, Ratain MJ, Innocenti F. Ramírez J, et al. Among authors: das s. Pharmacogenomics J. 2008 Apr;8(2):152-61. doi: 10.1038/sj.tpj.6500454. Epub 2007 Apr 17. Pharmacogenomics J. 2008. PMID: 17440429

4

Genetic factors affecting gene transcription and catalytic activity of UDP-glucuronosyltransferases in human liver.

Liu W, Ramírez J, Gamazon ER, Mirkov S, Chen P, Wu K, Sun C, Cox NJ, Cook E Jr, Das S, Ratain MJ. Liu W, et al. Among authors: das s. Hum Mol Genet. 2014 Oct 15;23(20):5558-69. doi: 10.1093/hmg/ddu268. Epub 2014 May 30. Hum Mol Genet. 2014. PMID: 24879639 Free PMC article.

5

Dose-finding and pharmacokinetic study to optimize the dosing of irinotecan according to the UGT1A1 genotype of patients with cancer.

Innocenti F, Schilsky RL, Ramírez J, Janisch L, Undevia S, House LK, Das S, Wu K, Turcich M, Marsh R, Karrison T, Maitland ML, Salgia R, Ratain MJ. Innocenti F, et al. Among authors: das s. J Clin Oncol. 2014 Aug 1;32(22):2328-34. doi: 10.1200/JCO.2014.55.2307. Epub 2014 Jun 23. J Clin Oncol. 2014. PMID: 24958824 Free PMC article. Clinical Trial.

6

Haplotype structure of the UDP-glucuronosyltransferase 1A1 promoter in different ethnic groups.

Innocenti F, Grimsley C, Das S, Ramírez J, Cheng C, Kuttab-Boulos H, Ratain MJ, Di Rienzo A. Innocenti F, et al. Among authors: das s. Pharmacogenetics. 2002 Dec;12(9):725-33. doi: 10.1097/00008571-200212000-00006. Pharmacogenetics. 2002. PMID: 12464801

7

A pharmacogenetic study of uridine diphosphate-glucuronosyltransferase 2B7 in patients receiving morphine.

Sawyer MB, Innocenti F, Das S, Cheng C, Ramírez J, Pantle-Fisher FH, Wright C, Badner J, Pei D, Boyett JM, Cook E Jr, Ratain MJ. Sawyer MB, et al. Among authors: das s. Clin Pharmacol Ther. 2003 Jun;73(6):566-74. doi: 10.1016/S0009-9236(03)00053-5. Clin Pharmacol Ther. 2003. PMID: 12811366 Clinical Trial.

8

Genetic variants in the UDP-glucuronosyltransferase 1A1 gene predict the risk of severe neutropenia of irinotecan.

Innocenti F, Undevia SD, Iyer L, Chen PX, Das S, Kocherginsky M, Karrison T, Janisch L, Ramírez J, Rudin CM, Vokes EE, Ratain MJ. Innocenti F, et al. Among authors: das s. J Clin Oncol. 2004 Apr 15;22(8):1382-8. doi: 10.1200/JCO.2004.07.173. Epub 2004 Mar 8. J Clin Oncol. 2004. PMID: 15007088

9

Haplotypes of variants in the UDP-glucuronosyltransferase1A9 and 1A1 genes.

Innocenti F, Liu W, Chen P, Desai AA, Das S, Ratain MJ. Innocenti F, et al. Among authors: das s. Pharmacogenet Genomics. 2005 May;15(5):295-301. doi: 10.1097/01213011-200505000-00004. Pharmacogenet Genomics. 2005. PMID: 15864130

10

Study of the genetic determinants of UGT1A1 inducibility by phenobarbital in cultured human hepatocytes.

Ramírez J, Komoroski BJ, Mirkov S, Graber AY, Fackenthal DL, Schuetz EG, Das S, Ratain MJ, Innocenti F, Strom SC. Ramírez J, et al. Among authors: das s. Pharmacogenet Genomics. 2006 Feb;16(2):79-86. doi: 10.1097/01.fpc.0000182784.77630.48. Pharmacogenet Genomics. 2006. PMID: 16424820

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