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Both total and phosphorylated tau are increased in Alzheimer's disease.
Sjögren M, Davidsson P, Tullberg M, Minthon L, Wallin A, Wikkelso C, Granérus AK, Vanderstichele H, Vanmechelen E, Blennow K. Sjögren M, et al. Among authors: vanmechelen e. J Neurol Neurosurg Psychiatry. 2001 May;70(5):624-30. doi: 10.1136/jnnp.70.5.624. J Neurol Neurosurg Psychiatry. 2001. PMID: 11309456 Free PMC article.
The cerebrospinal fluid levels of tau, growth-associated protein-43 and soluble amyloid precursor protein correlate in Alzheimer's disease, reflecting a common pathophysiological process.
Sjögren M, Davidsson P, Gottfries J, Vanderstichele H, Edman A, Vanmechelen E, Wallin A, Blennow K. Sjögren M, et al. Among authors: vanmechelen e. Dement Geriatr Cogn Disord. 2001 Jul-Aug;12(4):257-64. doi: 10.1159/000051268. Dement Geriatr Cogn Disord. 2001. PMID: 11351137
163 results