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Mechanism underlying the reduced positive inotropic effects of the phosphodiesterase III inhibitors pimobendan, adibendan and saterinone in failing as compared to nonfailing human cardiac muscle preparations.
von der Leyen H, Mende U, Meyer W, Neumann J, Nose M, Schmitz W, Scholz H, Starbatty J, Stein B, Wenzlaff H, et al. von der Leyen H, et al. Among authors: neumann j. Naunyn Schmiedebergs Arch Pharmacol. 1991 Jul;344(1):90-100. doi: 10.1007/BF00167387. Naunyn Schmiedebergs Arch Pharmacol. 1991. PMID: 1723153
Differential antagonism by 1,3-dipropylxanthine-8-cyclopentylxanthine and 9-chloro-2-(2-furanyl)-5,6-dihydro-1,2,4-triazolo(1,5-c)quinazolin-5-im ine of the effects of adenosine derivatives in the presence of isoprenaline on contractile response and cyclic AMP content in cardiomyocytes. Evidence for the coexistence of A1- and A2-adenosine receptors on cardiomyocytes.
Behnke N, Müller W, Neumann J, Schmitz W, Scholz H, Stein B. Behnke N, et al. Among authors: neumann j. J Pharmacol Exp Ther. 1990 Sep;254(3):1017-23. J Pharmacol Exp Ther. 1990. PMID: 2168481
Phosphodiesterase inhibition and positive inotropic effects.
Schmitz W, von der Leyen H, Meyer W, Neumann J, Scholz H. Schmitz W, et al. Among authors: neumann j. J Cardiovasc Pharmacol. 1989;14 Suppl 3:S11-4. doi: 10.1097/00005344-198914003-00003. J Cardiovasc Pharmacol. 1989. PMID: 2478797 Review.
1,772 results