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Competitive, reversible inhibition of cytosolic phospholipase A2 at the lipid-water interface by choline derivatives that partially partition into the phospholipid bilayer.
Burke JR, Witmer MR, Zusi FC, Gregor KR, Davern LB, Padmanabha R, Swann RT, Smith D, Tredup JA, Micanovic R, Manly SP, Villafranca JJ, Tramposch KM. Burke JR, et al. Among authors: tramposch km. J Biol Chem. 1999 Jul 2;274(27):18864-71. doi: 10.1074/jbc.274.27.18864. J Biol Chem. 1999. PMID: 10383382 Free article.
Biaryl diacid inhibitors of human s-PLA2 with anti-inflammatory activity.
Springer DM, Luh BY, Bronson JJ, McElhone KE, Mansuri MM, Gregor KR, Nettleton DO, Stanley PL, Tramposch KM. Springer DM, et al. Among authors: tramposch km. Bioorg Med Chem. 2000 May;8(5):1087-109. doi: 10.1016/s0968-0896(00)00047-x. Bioorg Med Chem. 2000. PMID: 10882020
48 results