Takenaka T - Search Results

1

Enzymatic and functional correction along with long-term enzyme secretion from transduced bone marrow hematopoietic stem/progenitor and stromal cells derived from patients with Fabry disease.

Takenaka T, Hendrickson CS, Tworek DM, Tudor M, Schiffmann R, Brady RO, Medin JA. Takenaka T, et al. Exp Hematol. 1999 Jul;27(7):1149-59. doi: 10.1016/s0301-472x(99)00050-8. Exp Hematol. 1999. PMID: 10390190 Free article.

2

Circulating alpha-galactosidase A derived from transduced bone marrow cells: relevance for corrective gene transfer for Fabry disease.

Takenaka T, Qin G, Brady RO, Medin JA. Takenaka T, et al. Hum Gene Ther. 1999 Aug 10;10(12):1931-9. doi: 10.1089/10430349950017293. Hum Gene Ther. 1999. PMID: 10466627

3

Long-term enzyme correction and lipid reduction in multiple organs of primary and secondary transplanted Fabry mice receiving transduced bone marrow cells.

Takenaka T, Murray GJ, Qin G, Quirk JM, Ohshima T, Qasba P, Clark K, Kulkarni AB, Brady RO, Medin JA. Takenaka T, et al. Proc Natl Acad Sci U S A. 2000 Jun 20;97(13):7515-20. doi: 10.1073/pnas.120177997. Proc Natl Acad Sci U S A. 2000. PMID: 10840053 Free PMC article.

4

Preselective gene therapy for Fabry disease.

Qin G, Takenaka T, Telsch K, Kelley L, Howard T, Levade T, Deans R, Howard BH, Malech HL, Brady RO, Medin JA. Qin G, et al. Among authors: takenaka t. Proc Natl Acad Sci U S A. 2001 Mar 13;98(6):3428-33. doi: 10.1073/pnas.061020598. Epub 2001 Mar 6. Proc Natl Acad Sci U S A. 2001. PMID: 11248095 Free PMC article.

5

Sequencing and characterization of the porcine α-galactosidase A gene: towards the generation of a porcine model for Fabry disease.

Yoshimitsu M, Higuchi K, Fan X, Takao S, Medin JA, Tei C, Takenaka T. Yoshimitsu M, et al. Among authors: takenaka t. Mol Biol Rep. 2011 Jun;38(5):3145-52. doi: 10.1007/s11033-010-9985-5. Epub 2010 Feb 4. Mol Biol Rep. 2011. PMID: 20131008

6

Identification of novel mutations in the α-galactosidase A gene in patients with Fabry disease: pitfalls of mutation analyses in patients with low α-galactosidase A activity.

Yoshimitsu M, Higuchi K, Miyata M, Devine S, Mattman A, Sirrs S, Medin JA, Tei C, Takenaka T. Yoshimitsu M, et al. Among authors: takenaka t. J Cardiol. 2011 May;57(3):345-53. doi: 10.1016/j.jjcc.2010.12.004. Epub 2011 Feb 17. J Cardiol. 2011. PMID: 21333496 Free article.

7

Lentivector transduction improves outcomes over transplantation of human HSCs alone in NOD/SCID/Fabry mice.

Pacienza N, Yoshimitsu M, Mizue N, Au BC, Wang JC, Fan X, Takenaka T, Medin JA. Pacienza N, et al. Among authors: takenaka t. Mol Ther. 2012 Jul;20(7):1454-61. doi: 10.1038/mt.2012.64. Epub 2012 Apr 3. Mol Ther. 2012. PMID: 22472949 Free PMC article.

8

Retrovirus-mediated correction of the metabolic defect in cultured Farber disease cells.

Medin JA, Takenaka T, Carpentier S, Garcia V, Basile JP, Segui B, Andrieu-Abadie N, Auge N, Salvayre R, Levade T. Medin JA, et al. Among authors: takenaka t. Hum Gene Ther. 1999 May 20;10(8):1321-9. doi: 10.1089/10430349950018003. Hum Gene Ther. 1999. PMID: 10365663

9

Alpha-galactosidase A-Tat fusion enhances storage reduction in hearts and kidneys of Fabry mice.

Higuchi K, Yoshimitsu M, Fan X, Guo X, Rasaiah VI, Yen J, Tei C, Takenaka T, Medin JA. Higuchi K, et al. Among authors: takenaka t. Mol Med. 2010 May-Jun;16(5-6):216-21. doi: 10.2119/molmed.2009.00163. Epub 2010 Feb 17. Mol Med. 2010. PMID: 20454522 Free PMC article.

10

Direct injection of kit ligand-2 lentivirus improves cardiac repair and rescues mice post-myocardial infarction.

Higuchi K, Ayach B, Sato T, Chen M, Devine SP, Rasaiah VI, Dawood F, Yanagisawa T, Tei C, Takenaka T, Liu PP, Medin JA. Higuchi K, et al. Among authors: takenaka t. Mol Ther. 2009 Feb;17(2):262-8. doi: 10.1038/mt.2008.244. Epub 2008 Nov 11. Mol Ther. 2009. PMID: 19002160 Free PMC article.

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