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Tropomyosin 3 expression leads to hypercontractility and attenuates myofilament length-dependent Ca(2+) activation.
Pieples K, Arteaga G, Solaro RJ, Grupp I, Lorenz JN, Boivin GP, Jagatheesan G, Labitzke E, DeTombe PP, Konhilas JP, Irving TC, Wieczorek DF. Pieples K, et al. Among authors: boivin gp. Am J Physiol Heart Circ Physiol. 2002 Oct;283(4):H1344-53. doi: 10.1152/ajpheart.00351.2002. Epub 2002 Jun 13. Am J Physiol Heart Circ Physiol. 2002. PMID: 12234784 Free article.
Dilated cardiomyopathy mutant tropomyosin mice develop cardiac dysfunction with significantly decreased fractional shortening and myofilament calcium sensitivity.
Rajan S, Ahmed RP, Jagatheesan G, Petrashevskaya N, Boivin GP, Urboniene D, Arteaga GM, Wolska BM, Solaro RJ, Liggett SB, Wieczorek DF. Rajan S, et al. Among authors: boivin gp. Circ Res. 2007 Jul 20;101(2):205-14. doi: 10.1161/CIRCRESAHA.107.148379. Epub 2007 Jun 7. Circ Res. 2007. PMID: 17556658
Molecular and functional characterization of a novel cardiac-specific human tropomyosin isoform.
Rajan S, Jagatheesan G, Karam CN, Alves ML, Bodi I, Schwartz A, Bulcao CF, D'Souza KM, Akhter SA, Boivin GP, Dube DK, Petrashevskaya N, Herr AB, Hullin R, Liggett SB, Wolska BM, Solaro RJ, Wieczorek DF. Rajan S, et al. Among authors: boivin gp. Circulation. 2010 Jan 26;121(3):410-8. doi: 10.1161/CIRCULATIONAHA.109.889725. Epub 2010 Jan 11. Circulation. 2010. PMID: 20065163 Free PMC article.
135 results