Muthuchamy M - Search Results

1

Mouse model of a familial hypertrophic cardiomyopathy mutation in alpha-tropomyosin manifests cardiac dysfunction.

Muthuchamy M, Pieples K, Rethinasamy P, Hoit B, Grupp IL, Boivin GP, Wolska B, Evans C, Solaro RJ, Wieczorek DF. Muthuchamy M, et al. Circ Res. 1999 Jul 9;85(1):47-56. doi: 10.1161/01.res.85.1.47. Circ Res. 1999. PMID: 10400910

2

Molecular and physiological effects of overexpressing striated muscle beta-tropomyosin in the adult murine heart.

Muthuchamy M, Grupp IL, Grupp G, O'Toole BA, Kier AB, Boivin GP, Neumann J, Wieczorek DF. Muthuchamy M, et al. J Biol Chem. 1995 Dec 22;270(51):30593-603. doi: 10.1074/jbc.270.51.30593. J Biol Chem. 1995. PMID: 8530495 Free article.

3

Molecular and physiological effects of alpha-tropomyosin ablation in the mouse.

Rethinasamy P, Muthuchamy M, Hewett T, Boivin G, Wolska BM, Evans C, Solaro RJ, Wieczorek DF. Rethinasamy P, et al. Among authors: muthuchamy m. Circ Res. 1998 Jan 9-23;82(1):116-23. doi: 10.1161/01.res.82.1.116. Circ Res. 1998. PMID: 9440710

4

Beta-tropomyosin overexpression induces severe cardiac abnormalities.

Muthuchamy M, Boivin GP, Grupp IL, Wieczorek DF. Muthuchamy M, et al. J Mol Cell Cardiol. 1998 Aug;30(8):1545-57. doi: 10.1006/jmcc.1998.0720. J Mol Cell Cardiol. 1998. PMID: 9737941

5

Correlation between myofilament response to Ca2+ and altered dynamics of contraction and relaxation in transgenic cardiac cells that express beta-tropomyosin.

Wolska BM, Keller RS, Evans CC, Palmiter KA, Phillips RM, Muthuchamy M, Oehlenschlager J, Wieczorek DF, de Tombe PP, Solaro RJ. Wolska BM, et al. Among authors: muthuchamy m. Circ Res. 1999 Apr 16;84(7):745-51. doi: 10.1161/01.res.84.7.745. Circ Res. 1999. PMID: 10205142

6

Altered hemodynamics in transgenic mice harboring mutant tropomyosin linked to hypertrophic cardiomyopathy.

Evans CC, Pena JR, Phillips RM, Muthuchamy M, Wieczorek DF, Solaro RJ, Wolska BM. Evans CC, et al. Among authors: muthuchamy m. Am J Physiol Heart Circ Physiol. 2000 Nov;279(5):H2414-23. doi: 10.1152/ajpheart.2000.279.5.H2414. Am J Physiol Heart Circ Physiol. 2000. PMID: 11045979 Free article.

7

Induction of endogenous myosin light chain 1 and cardiac alpha-actin expression in L6E9 cells by MyoD1.

Muthuchamy M, Pajak L, Wieczorek DF. Muthuchamy M, et al. J Biol Chem. 1992 Sep 15;267(26):18728-34. J Biol Chem. 1992. PMID: 1382061 Free article.

8

Developmental analysis of tropomyosin gene expression in embryonic stem cells and mouse embryos.

Muthuchamy M, Pajak L, Howles P, Doetschman T, Wieczorek DF. Muthuchamy M, et al. Mol Cell Biol. 1993 Jun;13(6):3311-23. doi: 10.1128/mcb.13.6.3311-3323.1993. Mol Cell Biol. 1993. PMID: 7684495 Free PMC article.

9

Exchange of beta- for alpha-tropomyosin in hearts of transgenic mice induces changes in thin filament response to Ca2+, strong cross-bridge binding, and protein phosphorylation.

Palmiter KA, Kitada Y, Muthuchamy M, Wieczorek DF, Solaro RJ. Palmiter KA, et al. Among authors: muthuchamy m. J Biol Chem. 1996 May 17;271(20):11611-4. doi: 10.1074/jbc.271.20.11611. J Biol Chem. 1996. PMID: 8662805 Free article.

10

Tropomyosin structure and function new insights.

Muthuchamy M, Rethinasamy P, Wieczorek DF. Muthuchamy M, et al. Trends Cardiovasc Med. 1997 May;7(4):124-8. doi: 10.1016/S1050-1738(97)00004-2. Trends Cardiovasc Med. 1997. PMID: 21235875

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