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Che-1 affects cell growth by interfering with the recruitment of HDAC1 by Rb.
Bruno T, De Angelis R, De Nicola F, Barbato C, Di Padova M, Corbi N, Libri V, Benassi B, Mattei E, Chersi A, Soddu S, Floridi A, Passananti C, Fanciulli M. Bruno T, et al. Among authors: di padova m. Cancer Cell. 2002 Nov;2(5):387-99. doi: 10.1016/s1535-6108(02)00182-4. Cancer Cell. 2002. PMID: 12450794 Free article.
Che-1 phosphorylation by ATM/ATR and Chk2 kinases activates p53 transcription and the G2/M checkpoint.
Bruno T, De Nicola F, Iezzi S, Lecis D, D'Angelo C, Di Padova M, Corbi N, Dimiziani L, Zannini L, Jekimovs C, Scarsella M, Porrello A, Chersi A, Crescenzi M, Leonetti C, Khanna KK, Soddu S, Floridi A, Passananti C, Delia D, Fanciulli M. Bruno T, et al. Among authors: di padova m. Cancer Cell. 2006 Dec;10(6):473-86. doi: 10.1016/j.ccr.2006.10.012. Cancer Cell. 2006. PMID: 17157788 Free article.
35 results