Osborne S - Search Results

1

Predictivity of an in vitro model for acute and chronic skin irritation (SkinEthic) applied to the testing of topical vehicles.

de Brugerolle de Fraissinette, Picarles V, Chibout S, Kolopp M, Medina J, Burtin P, Ebelin ME, Osborne S, Mayer FK, Spake A, Rosdy M, De Wever B, Ettlin RA, Cordier A. de Brugerolle de Fraissinette, et al. Among authors: osborne s. Cell Biol Toxicol. 1999 Apr;15(2):121-35. doi: 10.1023/a:1007577515215. Cell Biol Toxicol. 1999. PMID: 10408359

2

Pharmacokinetics of pimecrolimus, a novel nonsteroid anti-inflammatory drug, after single and multiple oral administration.

Scott G, Osborne SA, Greig G, Hartmann S, Ebelin ME, Burtin P, Rappersberger K, Komar M, Wolff K. Scott G, et al. Among authors: osborne sa. Clin Pharmacokinet. 2003;42(14):1305-14. doi: 10.2165/00003088-200342140-00006. Clin Pharmacokinet. 2003. PMID: 14606933 Clinical Trial.

3

The pharmacokinetics of the novel promotile drug, tegaserod, are similar in healthy subjects-male and female, elderly and young.

Appel-Dingemanse S, Horowitz A, Campestrini J, Osborne S, McLeod J. Appel-Dingemanse S, et al. Among authors: osborne s. Aliment Pharmacol Ther. 2001 Jul;15(7):937-44. doi: 10.1046/j.1365-2036.2001.00973.x. Aliment Pharmacol Ther. 2001. PMID: 11421867 Clinical Trial.

4

Tegaserod, a 5-HT4 receptor partial agonist, accelerates gastric emptying and gastrointestinal transit in healthy male subjects.

Degen L, Matzinger D, Merz M, Appel-Dingemanse S, Osborne S, Lüchinger S, Bertold R, Maecke H, Beglinger C. Degen L, et al. Among authors: osborne s. Aliment Pharmacol Ther. 2001 Nov;15(11):1745-51. doi: 10.1046/j.1365-2036.2001.01103.x. Aliment Pharmacol Ther. 2001. PMID: 11683688 Clinical Trial.

5

Multiple-dose pharmacokinetics confirm no accumulation and dose proportionality of the novel promotile drug tegaserod (HTF 919).

Appel-Dingemanse S, Hirschberg Y, Osborne S, Pommier F, McLeod J. Appel-Dingemanse S, et al. Among authors: osborne s. Eur J Clin Pharmacol. 2001 Mar;56(12):889-91. doi: 10.1007/s002280000239. Eur J Clin Pharmacol. 2001. PMID: 11317476 Clinical Trial.

6

Effect of meal timing not critical for the pharmacokinetics of tegaserod (HTF 919).

Zhou H, Khalilieh S, Lau H, Guerret M, Osborne S, Alladina L, Laurent AL, McLeod JF. Zhou H, et al. Among authors: osborne s. J Clin Pharmacol. 1999 Sep;39(9):911-9. doi: 10.1177/00912709922008524. J Clin Pharmacol. 1999. PMID: 10471981 Clinical Trial.

7

Tegaserod coadministration does not alter the pharmacokinetics of theophylline in healthy subjects.

Zhou H, Khalilieh S, Svendsen K, Pommier F, Osborne S, Appel-Dingemanse S, Lasseter K, McLeod JF. Zhou H, et al. Among authors: osborne s. J Clin Pharmacol. 2001 Sep;41(9):987-93. doi: 10.1177/00912700122010979. J Clin Pharmacol. 2001. PMID: 11549104 Clinical Trial.

8

The effects of tegaserod (HTF 919) on the pharmacokinetics and pharmacodynamics of digoxin in healthy subjects.

Zhou H, Horowitz A, Ledford PC, Hubert M, Appel-Dingemanse S, Osborne S, McLeod JF. Zhou H, et al. Among authors: osborne s. J Clin Pharmacol. 2001 Oct;41(10):1131-9. doi: 10.1177/00912700122012625. J Clin Pharmacol. 2001. PMID: 11583482 Clinical Trial.

9

Tegaserod pharmacokinetics are similar in patients with severe renal insufficiency and in healthy subjects.

Swan SK, Zhou H, Horowitz A, Alladina L, Hubert M, Appel-Dingemanse S, Osborne S, Lambrecht L, McLeod JF. Swan SK, et al. Among authors: osborne s. J Clin Pharmacol. 2003 Apr;43(4):359-64. doi: 10.1177/0091270003251823. J Clin Pharmacol. 2003. PMID: 12723456 Clinical Trial.

10

[3H]L-694,247 labels the 5-HT1D beta receptor in pig caudate membranes.

Heald A, Stanton JA, Osborne SA, Middlemiss DN, Beer MS. Heald A, et al. Among authors: osborne sa. Eur J Pharmacol. 1994 Oct 24;264(2):213-6. doi: 10.1016/0014-2999(94)00527-3. Eur J Pharmacol. 1994. PMID: 7851485

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